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Filtered Search Results
Medchemexpress LLC Zalunfiban dihydrochloride | 2815778-41-5 | 99.1% | 10 MG
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Zalunfiban dihydrochloride is a potent, selective platelet αIIbβ3 antagonist (IC50 45 nM) supplied as a high-purity solid for in vitro and in vivo research on platelet function and myocardial infarction.
- CAS number: 2815778-41-5
- Molecular formula: C16H20Cl2N8O2S
- Molecular weight: 459.35 g/mol
- Purity: 99.1%
- Appearance: Solid
- In vitro solubility: DMSO 10 mg/mL (21.77 mM) with sonication and warming
- Suggested storage: 4°C sealed, away from moisture; in solvent -80°C (6 months)
- Typical pack size: 10 mg
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Medchemexpress LLC (E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enoic acid | 122520-79-0 | MFCD09739079 | 99.7% | 205.17 g·mol⁻¹ | C10H7NO4 | 2 MG
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Tyrphostin AG30 is a small-molecule EGFR tyrosine kinase inhibitor (CAS 122520-79-0) used in biochemical and cellular studies to probe EGFR/c-ErbB signaling. It is supplied as a high-purity solid appropriate for solution preparation and in vitro testing.
- High purity: 99.7%.
- Target: EGFR tyrosine kinase; inhibits c-ErbB-induced self-renewal and STAT5 activation.
- Molecular formula C10H7NO4 and molecular weight 205.17 g·mol⁻¹.
- Available in milligram pack sizes for small-scale research use.
- Storage: powder -20 °C (long-term) or 4 °C (short-term); in solvent -80 °C recommended for extended stability.
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Medchemexpress LLC Imb-301 | 64009-84-3 | 99.1% | 5 MG
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Imb-301 is a small-molecule inhibitor of HIV-1 replication that binds human APOBEC3G (hA3G), disrupts the hA3G-Vif interaction, and inhibits Vif-mediated degradation of hA3G. It is supplied as a research reagent and intended for laboratory use only.
- Inhibits Vif-mediated degradation of hA3G.
- High purity (99.1%).
- Molecular weight 379.26 g/mol.
- CAS number 64009-84-3 for unambiguous identification.
- Supplied as an oil in a 5 MG quantity for laboratory use only.
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Sigma Aldrich Fine Chemicals Biosciences Phenol BioUltra, for molecular biology, TE-saturated, ~73% (T) | 108-95-2 | MFCD00002143 | 250ML
Phenol BioUltra, for molecular biology, TE-saturated, ~73% (T) | Purity: ~73% (T) | Mol Wt: 94.11 | 108-95-2 | MFCD00002143 | 250ML
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Sigma Aldrich Fine Chemicals Biosciences Phenol solution | 108-95-2 | MFCD00002143 | 400 mL
Phenol solution | Mol Wt: 94.11 | 108-95-2 | MFCD00002143 | 400 mL
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Sigma Aldrich Fine Chemicals Biosciences Diethylstilbestrol >=99% (HPLC) | 56-53-1 | MFCD00002373 | 5G
Diethylstilbestrol >=99% (HPLC) | Purity: >=99% (HPLC) | Mol Wt: 268.35 | 56-53-1 | MFCD00002373 | 5G
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Medchemexpress LLC 7-hydroxy-2,3,4,5-tetrahydro-benzofuro[2,3-c]azepin-1-one | 521937-07-5 | 99.1% | 100 MG
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This small-molecule inhibitor targets protein kinase D (PKD) isoforms with submicromolar potency and is supplied as a white to off-white solid for research use.
- Inhibits PKD1, PKD2, and PKD3 with IC50s of 182 nM, 280 nM, and 227 nM.
- Purity 99.1% (HPLC).
- Molecular formula C12H11NO3; molecular weight 217.22 g/mol.
- Soluble in DMSO at 100 mg/mL; in vivo formulations achievable at ≥2.5 mg/mL using recommended vehicles.
- Appearance white to off-white solid.
- Storage: powder -20°C up to 3 years; in solvent -80°C up to 2 years.
- Supplied as a 100 mg pack; also available in smaller and larger sizes or as 10 mM DMSO solutions.
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Medchemexpress LLC SN-011 (STING Inhibitor) | 2249435-90-1 | 99.9% | C25H19FN2O4S | 50 MG
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SN-011 is a potent and selective mouse and human STING inhibitor, with an IC50 of 76 nM for STING signaling. This compound functions by competing with cyclic dinucleotide (CDN) for the binding pocket of the STING dimer, thereby blocking CDN binding and subsequent STING activation. It is intended for research pertaining to STING-driven autoimmune and inflammatory diseases.
- Potent and selective mouse and human STING inhibitor
- IC50 of 76 nM for STING signaling
- Blocks cyclic dinucleotide (CDN) binding and STING activation
- Useful for research of STING-driven autoimmune and inflammatory diseases
- Inhibits 2′3′-cGAMP-induced Ifnb expression in multiple cell types
- Suppresses STING oligomerization, phosphorylation, and ER-to-Golgi translocation
- Inhibits inflammation and autoimmunity in Trex1-/- mice, improving survival
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Medchemexpress LLC Procyanidin B3 | 23567-23-9 | 1 MG
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Procyanidin B3 is a natural product known for its antioxidant activity, oral bioavailability, and ability to penetrate the blood-brain barrier. It acts as a selective inhibitor of histone acetyltransferase (HAT), specifically by inhibiting p300 HAT-mediated acetylation of the androgen receptor. This product also helps alleviate intervertebral disc degeneration (IVDD) by inhibiting the formation of the TLR4/MD-2 complex.
- Exhibits antioxidant activity
- Possesses oral bioavailability and blood-brain barrier penetration
- Functions as a selective histone acetyltransferase (HAT) inhibitor
- Specifically inhibits p300 HAT-mediated acetylation of the androgen receptor
- Alleviates intervertebral disc degeneration (IVDD) by inhibiting TLR4/MD-2 complex formation
- Applicable for research in prostate cancer and arthritis
- Does not affect HDAC or HMT (histone methyltransferase)
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eMolecules Ambeed | Diosmetin | 5g | 490501205 | A124051 | 96.000 | 520-34-3 | MFCD00017425 | 300.266 | C16H12O6
Ambeed | Diosmetin | 5g | 490501205 | A124051 | 96.000 | 520-34-3 | MFCD00017425 | 300.266 | C16H12O6
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Medchemexpress LLC Oxyresveratrol 2-O-β-D-glucopyranoside | 392274-22-5 | 5 MG
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Oxyresveratrol 2-O-β-D-glucopyranoside is a phenolic compound isolated from the root of *Morus nigra*. It functions as an effective tyrosinase inhibitor with an IC50 of 29.75 μM. This product is intended for research use only.
- Phenolic compound isolated from *Morus nigra* root
- Effective tyrosinase inhibitor
- Intended for research use only
- Purity: 98.93%
- Molecular weight: 406.38
- Chemical formula: C20H22O9
- Appearance: White to off-white solid
- Target: Tyrosinase
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Medchemexpress LLC [10]-Shogaol | 36752-54-2 | 5 MG
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[10]-Shogaol is an orally active antioxidant extracted from ginger (*Zingiber officinale*). It demonstrates various biological activities including anti-inflammatory and anticancer effects. It is suitable for laboratory research in immunology, inflammation, and anti-infection pathways.
- Inhibits COX-2 and NF-κB phosphorylation
- Reduces proinflammatory cytokines such as IL-1β and IL-6
- Exhibits anti-inflammatory properties
- Demonstrates anticancer effects against Docetaxel-resistant prostate cancer
- Shows larvicidal activity against *Angiostrongylus cantonensis* L5 larvae
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Medchemexpress LLC Plicamycin (Mithramycin A) | 18378-89-7 | 99.5% | C52H76O24 | 100 MG
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Plicamycin (Mithramycin A) | 18378-89-7 | 99.5% | C52H76O24 | 100 MG
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Medchemexpress LLC Plicamycin (Mithramycin A) | 18378-89-7 | MFCD00135618 | 99.46% | C52H76O24 | 50 MG
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Plicamycin (Mithramycin A) is a selective specificity protein 1 (Sp1) inhibitor that inhibits the growth of various cancers by decreasing Sp1 protein. It also inhibits GSTM2 promoter activity and protein expression. It has demonstrated antitumorigenic activity in xenograft models, reducing tumor volume and weight with minimal toxicity.
- Selective specificity protein 1 (Sp1) inhibitor
- Inhibits growth of various cancers by decreasing Sp1 protein
- Inhibits GSTM2 promoter activity and protein expression
- Induces proteasome-dependent degradation of Sp1 protein
- Suppresses cervical cancer growth via a DR5/caspase-8/Bid signaling pathway
- Demonstrates concentration-dependent inhibition of HEp-2 and KB cell growth
- Causes significant DNA fragmentation
- Antitumorigenic activity in xenograft models
- Reduces tumor volume and weight with minimal toxicity
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Medchemexpress LLC Apigenin 7-glucoside | 578-74-5 | MFCD00016787 | 432.38 | 100 MG
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Apigenin 7-glucoside | 578-74-5 | MFCD00016787 | 432.38 | 100 MG
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